N,N'-Bis(3-Aminopropyl)-2,2-Difluorobutane-1,4-Diamine
CAS: 111397-41-2
Ref. 3D-FB93937
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Product Information
- 1,4-Butanediamine, N,N'-bis(3-aminopropyl)-2,2-difluoro-
- N,N'-bis(3-aminopropyl)-2,2-difluorobutane-1,4-diamine
N,N'-Bis(3-Aminopropyl)-2,2-Difluorobutane-1,4-Diamine is a prodrug that is hydrolyzed in vivo to 2,2-difluoro-N-(3-aminopropyl)butane diamine. It has been shown to be effective against bladder cancer cells and enhances the antitumor activity of spermine synthase inhibitors. N,N'-Bis(3-Aminopropyl)-2,2-Difluorobutane-1,4-Diamine has also been shown to inhibit polyamine oxidase (PAO). This inhibition leads to an increase in the levels of endogenous amines such as ornithine and putrescine in tissues.
Chemical properties
Technical inquiry about: 3D-FB93937 N,N'-Bis(3-Aminopropyl)-2,2-Difluorobutane-1,4-Diamine
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