1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone
CAS: 1378387-81-5
Ref. 3D-FB95439
1g | To inquire | ||
250mg | To inquire | ||
500mg | To inquire |
Product Information
- 1-(7-Bromo-9,9-difluorofluoren-2-yl)-2-chloroethanone
- 1-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloro-Ethanone
- Ethanone, 1-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloro-
1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone is a target product that is synthesized from 2-amino-5 bromobenzoic acid and chlorination of phenylboronic acid. The synthesis of this compound involves the diazotization of 1-(7-bromo-9,9 difluoro 9H fluoren 2 yl) ethanone with sodium nitrite in the presence of hydrochloric acid and sodium hydroxide. This compound is then coupled with 2 chloroethanol to form the title product. The coupling reaction includes stirring at room temperature for 6 hours with sodium carbonate as a base. The chlorination reaction follows by adding bromine dropwise to a solution of the target product in a solvent such as ethanol or acetonitrile. The ester hydrolysis occurs when the target product
Chemical properties
Technical inquiry about: 3D-FB95439 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone
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