Product Information
- 4-Cyclopropylphenyl methyl ether
- Benzene, 1-Cyclopropyl-4-Methoxy-
- p-Cyclopropylanisole
a-Cyclopropyl-4-methoxybenzene (1) is a dinitrogen tetroxide adduct of the Grignard reagent, which can be used as a cross-coupling agent to form cyclopropanes. 1 is activated by the chloride ion and an electron-deficient acceptor, such as an aryl chloride or benzyl group. The reaction proceeds in the presence of a nucleophile, such as an alcohol or amine, and transfer agent such as triethylsilane. The synthesis of cyclopropanes can be achieved through a cross-coupling reaction between two substituted phenyl chlorides and one equivalent of an alcohol or amine. This synthetic route avoids the formation of thermally unstable organometallic intermediates.
Chemical properties
Technical inquiry about: 3D-FC00025 a-Cyclopropyl-4-methoxybenzene
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