2-Chloro-1,4-phenylenediamine sulfate

CAS: 61702-44-1

Ref. 3D-FC00621

Product Information

• Name: 2-Chloro-1,4-phenylenediamine sulfate
• Synonyms: 1,4-Benzenediamine, 2-chloro-, sulfate (1:1), 2-Chloro-1,4-Phenylenediamine Sulfate, 2-Chloro-1,4-benzenediamine sulfate, 2-Chloro-1,4-diaminobenzene monosulfate, 2-Chlorobenzene-1,4-Diammonium Sulphate, 2-Chlorobenzene-1,4-diamine; sulfuric acid, Chloropphenylenediaminesulfate, O-Chlono-p-phenylene diamine sulfate, O-Chloro-P-Phenylene Diamine Sulfate, S-(5-methyl-1,3,4-thiadiazol-2-yl) 9H-carbazol-9-ylethanethioate

Description

2-Chloro-1,4-phenylenediamine sulfate (2CPDS) is a proximal tubule toxicant that can impair renal function. 2CPDS has been shown to be a dietary nephrotoxin in rats and mice. Proximal tubules from animals treated with 2CPDS have been found to contain high levels of urea nitrogen and creatinine. The mechanism of action for 2CPDS is not fully understood but it is believed that the proximal tubules are damaged by an unknown mechanism. The toxicity of 2CPDS has also been observed in humans, as serum levels were found to increase following ingestion of a single dose. Animal studies have shown that 2CPDS binds to aromatic hydrocarbons and may act as an allergen or antigen.

• Brand: Biosynth

Chemical properties

• Molecular weight: 240.67 g/mol
• Formula: C₆H₉ClN₂O₄S
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C6H7ClN2.H2O4S/c7-5-3-4(8)1-2-6(5)9;1-5(2,3)4/h1-3H,8-9H2;(H2,1,2,3,4)
• InChI key: InChIKey=GQFGHCRXPLROOF-UHFFFAOYSA-N
• SMILES: Nc1ccc(N)c(Cl)c1.O=S(=O)(O)O