5-Chloro-2-thiophenesulfonyl chloride

CAS: 2766-74-7

Ref. 3D-FC03132

Product Information

• Name: 5-Chloro-2-thiophenesulfonyl chloride
• Synonyms: 2-Chloro-5-[$L^{2}-Chloranylidene(Dioxo)-$L^{7}-Sulfanyl]Thiophene, 2-Chloro-5-chlorosulfonylthiophene, 2-Chlorothiophene-5-sulfonyl chloride, 2-Thiophenesulfonyl chloride, 5-chloro-, 5-Chloro-2-thienylsulfonyl chloride
• CAS: 2766-74-7

Description

5-Chloro-2-thiophenesulfonyl chloride is a chemical compound that is used as an inhibitor of γ-secretase. It binds to the active conformation of the enzyme, blocking its activity and reducing the production of β-amyloid. It also inhibits the catalysis of proteolytic enzymes by azides, which may be involved in other processes such as chemokine production. 5-Chloro-2-thiophenesulfonyl chloride is a white crystalline solid that has a melting point of about 117°C and no odor at room temperature.

• Brand: Biosynth

Chemical properties

• Molecular weight: 217.09 g/mol
• Formula: C₄H₂Cl₂O₂S₂
• Purity: Min. 95%
• InChI: InChI=1S/C4H2Cl2O2S2/c5-3-1-2-4(9-3)10(6,7)8/h1-2H
• InChI key: InChIKey=SORSTNOXGOXWAO-UHFFFAOYSA-N
• SMILES: O=S(=O)(Cl)c1ccc(Cl)s1