Product Information
Name:
5-Chloro-2-benzimidazolone
Synonyms:
- 5-Chloro-2-hydroxbenzimidazole
- 2H-benzimidazol-2-one, 5-chloro-1,3-dihydro-
- 5-Chloro-1H-benzoimidazol-2-ol
- 5-Chloro-1,3-dihydro-2H-benzimidazol-2-one
Description:
5-Chloro-2-benzimidazolone is an aminoguanidine derivative that inhibits the induction of the inducible nitric oxide synthase (iNOS) and prevents the secretion of nitric oxide. It also inhibits macrophages, endothelial cells, and neuronal cells. The inhibitory activity of 5-chloro-2-benzimidazolone on macrophages has been shown to be selective for lipopolysaccharide (LPS)-induced over LPS/interleukin 1β induced or LPS/tumor necrosis factor α induced. It also has a high selectivity for inhibiting iNOS in mouse macrophages over other iNOS isoforms.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
168.58 g/mol
Formula:
C7H5ClN2O
Purity:
Min. 95%
InChI:
InChI=1S/C7H5ClN2O/c8-4-1-2-5-6(3-4)10-7(11)9-5/h1-3H,(H2,9,10,11)
InChI key:
InChIKey=QIGIQLYKEULMQQ-UHFFFAOYSA-N
SMILES:
O=c1[nH]c2ccc(Cl)cc2[nH]1
MDL:
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