2-Chloro-N-(2-chloro-4-methyl-3-pyridinyl)-3-pyridinecarboxamide

CAS: 133627-46-0

Ref. 3D-FC09796

Product Information

• Name: 2-Chloro-N-(2-chloro-4-methyl-3-pyridinyl)-3-pyridinecarboxamide
• Synonyms: 1,3-Isobenzofurandione, 5-Methoxy-, 2-Chloro-N-(2-Chloro-4-Methylpyridin-3-Yl)Nicotinamide, 2-Chloro-N-(2-chloro-4-methyl-3-pyridinyl)-3-pyridine carboxamide, 2-Chloro-N-(2-chloro-4-methyl-3-pyridyl)-3-pyridine carboxamide, 2-chloro-N-(2-chloro-4-methylpyridin-3-yl)pyridine-3-carboxamide, 3-Pyridinecarboxamide, 2-chloro-N-(2-chloro-4-methyl-3-pyridinyl)-, 5-Methoxy-2-benzofuran-1,3-dion, 5-Methoxy-2-benzofuran-1,3-dione, Picnic
• CAS: 133627-46-0

Description

2-Chloro-N-(2-chloro-4-methyl-3-pyridinyl)-3-pyridinecarboxamide is a prodrug that is metabolized to nevirapine, its active form. It is an inorganic base and an aromatic hydrocarbon. The optimal reaction temperature for this compound is around 20°C. 2-Chloro-N-(2-chloro-4-methyl-3-pyridinyl)-3-pyridinecarboxamide has been shown to be catalytic in the presence of acids or bases and can be used as a prodrug to produce nevirapine. This prodrug has been shown to have antiretroviral activity against HIV strains that are resistant to other drugs.

• Brand: Biosynth

Chemical properties

• Molecular weight: 282.13 g/mol
• Formula: C₁₂H₉Cl₂N₃O
• Purity: Min. 95%
• InChI: InChI=1S/C12H9Cl2N3O/c1-7-4-6-16-11(14)9(7)17-12(18)8-3-2-5-15-10(8)13/h2-6H,1H3,(H,17,18)
• InChI key: InChIKey=UVCHGYJPZGYMSW-UHFFFAOYSA-N
• SMILES: Cc1ccnc(Cl)c1NC(=O)c1cccnc1Cl