2-Chloro-4'-fluoroacetophenone

CAS: 456-04-2

Ref. 3D-FC101920

Product Information

• Name: 2-Chloro-4'-fluoroacetophenone
• Synonyms: 2-Chloro-1-(4-fluorophenyl)-1-ethanone, 2-Chloro-1-(4-fluorophenyl)ethanone, 2-Chloro-4'-fluoro acetophenone, 4-Fluorophenacyl chloride, 4′-Fluoro-2-chloroacetophenone, Acetophenone, 2-chloro-4′-fluoro-, Chloromethyl 4-fluorophenyl ketone, Ethanone, 2-chloro-1-(4-fluorophenyl)-, Omega-Chloro-4-Fluoroacetophenone, alpha.-Chloro-p-Fluoroacetophenone, p-Fluorophenacyl chloride, Α-Chloro-4'-Fluoroacetophenone, α-Chloro-p-fluoroacetophenone
• CAS: 456-04-2

Description

2-Chloro-4'-fluoroacetophenone is a chemical that is used as a dehydrating agent in organic synthesis. It is also used for the synthesis of trifluoromethylthiolation products and has been shown to be an important reagent for removing chlorinated organic compounds from wastewater. This compound has been found to react with nucleophilic compounds, such as chloride, by forming the corresponding 2-chloro-4'-fluoroacetophenone chloride in high yield. The reaction time and temperature are determined by the desired product. The mechanism of this reaction involves formation of a dihedral intermediate with fluorine acting as the nucleophile. 2-Chloro-4'-fluoroacetophenone can be synthesized biologically by microorganisms such as Bacillus subtilis.
2-Chloro-4'-fluoroacetophenone is an important precursor molecule in biomolecular research because it can be used to produce fluoroac

• Brand: Biosynth

Chemical properties

• Molecular weight: 172.58 g/mol
• Formula: C₈H₆ClFO
• Purity: Min. 95%
• InChI: InChI=1S/C8H6ClFO/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2
• InChI key: InChIKey=UJZWJOQRSMOFMA-UHFFFAOYSA-N
• SMILES: O=C(CCl)c1ccc(F)cc1