(3-chloro-4-fluorophenyl)boronic Acid

CAS: 144432-85-9

Ref. 3D-FC104918

Product Information

• Name: (3-chloro-4-fluorophenyl)boronic Acid
• Synonyms: 3-Chloro-4-fluorobenzeneboronic acid, 4-Fluoro-3-Chlorophenylboronic Acid, (3-Chloro-4-Fluorophenyl)-Boronic Acid

Description

3-Chloro-4-fluorophenyl)boronic acid (3CFPBA) is a boronic acid that is used in asymmetric synthesis. It has high lipophilicity and can be taken up by the brain. 3CFPBA has been shown to bind to naphthalene, which is a natural compound, with a binding constant of 2.6 x 10^10 M^-1. This molecule has been found to inhibit the production of beta amyloid peptides in Alzheimer's disease . 3CFPBA also binds to other heterocycles such as furan and pyrrole, which are found in molecules such as phenol and benzene respectively.

• Brand: Biosynth

Chemical properties

• Molecular weight: 174.36 g/mol
• Formula: C₆H₅BClFO₂
• Purity: Min. 95%
• InChI: InChI=1S/C6H5BClFO2/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3,10-11H
• InChI key: InChIKey=WJDZZXIDQYKVDG-UHFFFAOYSA-N
• SMILES: OB(O)c1ccc(F)c(Cl)c1