Characteristic MSH-Tetrapeptide
CAS: 4289-02-5
Ref. 3D-FC109086
| 5mg | 235.00 € | ||
| 10mg | 385.00 € | ||
| 25mg | 683.00 € | ||
| 50mg | 1,066.00 € | ||
| 100mg | 1,844.00 € |
Product Information
- H-His-Phe-Arg-Trp-OH H-HFRW-OH
The melanocortin-4 receptor (MC4R) is a G protein-coupled receptor that mediates the protective and cytoprotective activities of endogenous melanocortins. This receptor has been shown to be an important target for neuroprotective agents. The MC4R is expressed in the central nervous system, peripheral nervous system, and other tissues where it may have a role in regulating energy homeostasis. The N-terminal amino acid sequence of the human MC4R ligand is H-His-Phe-Arg-Trp-OH. This peptide has been shown to have potent agonist potency at the MC4R with a Kd of 0.2 nM and an EC50 of 2 nM.
Chemical properties
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