Product Information
- ?-Conotoxin El
- Conus ermineus
- free acidH-Arg-Asp-Hyp-Cys-Cys-Tyr-His-Pro-Thr-Cys-Asn-Met-Ser-Asn-Pro-Gln-Ile-Cys-OH trifluoroacet ate salt (Disulfide bonds between Cys4 and Cys10/Cys5 and Cys18)
Alpha-conotoxin EI is an analog of the amino acid alpha-conotoxin. It is a potent inhibitor of acetylcholine release from nerve terminals in a competitive manner, and it has been shown to be active against Stenotrophomonas maltophilia and other bacterial infections. This analog binds to the receptor binding site on acetylcholine receptors, exhibiting diagnostic properties as well as potent inhibition of agonist binding. Alpha-conotoxin EI is not orally active due to its strong hydrolysis by esterases when taken orally. However, it can be administered intravenously or intramuscularly with high bioavailability. The drug also exhibits anti-inflammatory properties that are thought to be due to its ability to inhibit prostaglandin synthesis.
Chemical properties
Technical inquiry about: 3D-FC110224 Alpha-Conotoxin EI (free acid) trifluoroacetate salt
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