2-[(4-Chlorophenyl)amino]acetohydrazide

CAS: 2371-31-5

Ref. 3D-FC115456

Product Information

• Name: 2-[(4-Chlorophenyl)amino]acetohydrazide
• Synonyms: Glycine, N-(p-chlorophenyl)-, hydrazide, (4-Chloro-phenylamino)-acetic acid hydrazide, N-(4-Chlorophenyl)glycine hydrazide, NSC 190329, Glycine, N-(4-chlorophenyl)-, hydrazide

Description

2-[(4-Chlorophenyl)amino]acetohydrazide (4-CPAH) is a polymerization inhibitor that has been shown to have anticancer activity against cancer cells. It inhibits the formation of microtubules, which are important for cell division. 4-CPAH binds to the active site of tubulin, preventing polymerization and therefore inhibiting cell division. This drug has been tested on Molt-4 tumor cells and found to be effective in inhibiting their growth. In addition, 4-CPAH has shown no toxicity in mice at doses up to 5g/kg.

• Brand: Biosynth

Chemical properties

• Molecular weight: 199.64 g/mol
• Formula: C₈H₁₀ClN₃O
• Purity: Min. 95%
• InChI: InChI=1S/C8H10ClN3O/c9-6-1-3-7(4-2-6)11-5-8(13)12-10/h1-4,11H,5,10H2,(H,12,13)
• InChI key: InChIKey=RGWSDFHTYZOJAY-UHFFFAOYSA-N
• SMILES: NNC(=O)CNc1ccc(Cl)cc1