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2-Chloro 7H-Pyrrolo[2,3-d]pyrimidine
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2-Chloro 7H-Pyrrolo[2,3-d]pyrimidine

CAS: 335654-06-3

Ref. 3D-FC11980

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Estimated delivery in United States, on Thursday 27 Jun 2024

Product Information

Name:
2-Chloro 7H-Pyrrolo[2,3-d]pyrimidine
Synonyms:
  • 7H-pyrrolo[2,3-d]pyrimidine,2-chloro-
  • 1H-Pyrrolo[2,3-d]pyrimidine, 2-chloro-
  • 2-Chloro-1H-pyrrolo[2,3-d]pyrimidine
Description:

2-Chloro 7H-Pyrrolo[2,3-d]pyrimidine is a pyrrolopyrimidine that inhibits the transcription factor NF-κB. It has been shown to inhibit the transcription of IL-4 and IL-5 in eosinophils. This inhibition was found to be mediated by the inhibition of NF-κB activity. The molecule has also been shown to have antiinflammatory properties in vitro. 2-Chloro 7H-Pyrrolo[2,3-d]pyrimidine is orally bioavailable and can be used for research purposes. In addition, this molecule can be synthesized using palladium catalysis in crosscoupling reactions.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
153.57 g/mol
Formula:
C6H4ClN3
Purity:
Min. 95%
InChI:
InChI=1S/C6H4ClN3/c7-6-9-3-4-1-2-8-5(4)10-6/h1-3H,(H,8,9,10)
InChI key:
InChIKey=HJOQGBBHVRYTDX-UHFFFAOYSA-N
SMILES:
Clc1ncc2cc[nH]c2n1
MDL:
Melting point:
Boiling point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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