1-Cyclohexyl-1H-pyrazol-5-amine

CAS: 3528-50-5

Ref. 3D-FC121828

Product Information

• Name: 1-Cyclohexyl-1H-pyrazol-5-amine
• Synonyms: 1H-pyrazol-5-amine, 1-cyclohexyl-

Description

1-Cyclohexyl-1H-pyrazol-5-amine is a potent inhibitor of human cytochrome P450 enzymes. It can be used to study the inhibition of these enzymes and their interactions with other compounds. 1-Cyclohexyl-1H-pyrazol-5-amine can also be used to study the binding sites on human cytochrome P450, which are located near the active site. The inhibition of human CYP2D6 by 1-cyclohexyl-1H pyrazol 5 amine has been studied extensively in kinetic studies, and it has been found that this compound does not interact with CYP2D6 at its active site but instead interacts with a phenyl group on the enzyme. This interaction causes a decrease in the affinity of CYP2D6 for substrates such as tyrosine hydroxylase, resulting in an increase in the rate of turnover and metabolism of certain drugs.

• Brand: Biosynth

Chemical properties

• Molecular weight: 165.24 g/mol
• Formula: C₉H₁₅N₃
• Purity: Min. 95%
• InChI: InChI=1S/C9H15N3/c10-9-6-7-11-12(9)8-4-2-1-3-5-8/h6-8H,1-5,10H2
• InChI key: InChIKey=PTQWQGFQOJOBJK-UHFFFAOYSA-N
• SMILES: Nc1ccnn1C1CCCCC1