6-Chloro-5-nitronicotinic acid
CAS: 7477-10-3
Ref. 3D-FC140472
1g | Discontinued | ||
2g | Discontinued | ||
5g | Discontinued | ||
10g | Discontinued | ||
25g | Discontinued |
Product Information
- 3-Pyridinecarboxylic acid, 6-chloro-5-nitro-
- 2-Chloro-3-nitro-5-pyridinecarboxylic acid
6-Chloro-5-nitronicotinic acid (6CNA) is a nicotinic acetylcholine receptor agonist that has been synthesized. It is used as an intermediate in the synthesis of other compounds, such as morpholine and acetylcholine. 6CNA binds to the primary amines on the surface of rat brain cells and causes their deamination, which results in the release of nitric oxide (NO). NO activates guanylate cyclase, leading to increased production of cyclic guanosine monophosphate (cGMP). This can lead to smooth muscle relaxation and dilated blood vessels. 6CNA also binds to chloride ions and alkylates them, forming a stable complex with high affinity for chloride ions.