3-Chloro-6-phenylpyridazine

CAS: 20375-65-9

Ref. 3D-FC140615

Product Information

• Name: 3-Chloro-6-phenylpyridazine
• CAS: 20375-65-9

Description

3-Chloro-6-phenylpyridazine is a butyrophenone that binds to the 5-ht2a receptor, which is an important neurotransmitter receptor in the brain. 3-Chloro-6-phenylpyridazine has been shown to inhibit the binding of [3H]5-HT to rat cortical membranes at concentrations of 10 μM. However, it has low efficiency and an ancillary effect on this receptor. 3-Chloro-6-phenylpyridazine also binds to nicotinic acetylcholine receptors, which are important for the transmission of nerve impulses. This drug has a profile that is similar to α7 nicotinic acetylcholine (α7nAChR) test compounds, such as dihydrodiisopropylamine (DHA). DHA inhibits chloride currents through α7nAChR channels and its effects are blocked by 3-[

• Brand: Biosynth

Chemical properties

• Molecular weight: 190.63 g/mol
• Formula: C₁₀H₇ClN₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H7ClN2/c11-10-7-6-9(12-13-10)8-4-2-1-3-5-8/h1-7H
• InChI key: InChIKey=BUBRFWDEAVIFMV-UHFFFAOYSA-N
• SMILES: Clc1ccc(-c2ccccc2)nn1