2-Chloro-6-methoxyquinazoline

CAS: 850424-11-2

Ref. 3D-FC142622

Product Information

• Name: 2-Chloro-6-methoxyquinazoline

Description

2-Chloro-6-methoxyquinazoline is a quinazoline derivative that is an inhibitor of the B-Raf protein kinase. This drug has been shown to inhibit the growth of cells in vitro, where it selectively inhibits the BRAFV600E mutant form of the kinase. The pharmacokinetic properties were determined for this drug and found to be similar for both healthy subjects and patients with advanced cancer, suggesting that 2-chloro-6-methoxyquinazoline may have potential as a treatment for advanced cancer.

• Brand: Biosynth

Chemical properties

• Molecular weight: 194.62 g/mol
• Formula: C₉H₇ClN₂O
• Purity: Min. 95%
• Color/Form: Slightly Yellow Powder
• InChI: InChI=1S/C9H7ClN2O/c1-13-7-2-3-8-6(4-7)5-11-9(10)12-8/h2-5H,1H3
• InChI key: InChIKey=NKHDIWOWDNCSLS-UHFFFAOYSA-N
• SMILES: COc1ccc2nc(Cl)ncc2c1