6-Chloro-5-nitropyrimidin-4-amine

CAS: 4316-94-3

Ref. 3D-FC144258

Product Information

• Name: 6-Chloro-5-nitropyrimidin-4-amine
• Synonyms: 4-Amino-5-nitro-6-chloropyrimidine, 4-Amino-6-chloro-5-nitropyrimidine, 4-Chloro-5-nitro-6-pyrimidinylamine, 6-Chloro-5-nitro-4-pyrimidinamine, NSC 401941, Pyrimidine, 4-amino-6-chloro-5-nitro-, Pyrimidine,4-amino-6-chloro-5-nitro- (6CI,7CI,8CI)
• CAS: 4316-94-3

Description

6-Chloro-5-nitropyrimidin-4-amine is a potent inhibitor of receptor tyrosine kinases, which are important for the growth and proliferation of cells. It has been shown to inhibit the growth of terminal alkynes in bacteria, such as Piricularia (an organism that causes ear infections). 6-Chloro-5-nitropyrimidin-4-amine also inhibits the activity of glycosylamines, which are enzymes that catalyze the formation of glycans. The inhibitory effect of 6-chloro-5 nitropyrimidin-4 amine on these enzymes may be due to its ability to trap formamide and other amines in an irreversible reaction.
6-Chloro-5 nitropyrimidin 4 amine has been shown to have potent inhibitory activity against toll like receptors. This inhibition prevents the activation of NFkB and subsequent inflammatory responses.

• Brand: Biosynth

Chemical properties

• Molecular weight: 174.55 g/mol
• Formula: C₄H₃ClN₄O₂
• Purity: Min. 95%