Cevimeline, hydrochloridesalt

CAS: 107233-08-9

Ref. 3D-FC146883

Product Information

• Name: Cevimeline, hydrochloridesalt
• Synonyms: (2R,2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane], (±)-cis-2-Methylspiro[1,3-oxathiolane-5,3′-quinuclidine], 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine, Af 102B, Cevimeline [INN], Fks 508, Hsdb 7286, Sni 2011, Spiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)-oxathiolane), 2'-methyl-, (2'R,3R)-rel-, Spiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)-oxathiolane), 2'-methyl-, cis-, Spiro[1-azabicyclo[2.2.2]octane-3,5′-[1,3]oxathiolane], 2′-methyl-, (2′R,3R)-rel-, Unii-K9V0Cdq56E, rel-(2′R,3R)-2′-Methylspiro[1-azabicyclo[2.2.2]octane-3,5′-[1,3]oxathiolane], Cevimeline

Description

Cevimeline is a cholinergic agent that is used to treat salivary gland dysfunction in geriatric patients and autoimmune diseases. It has been shown to have a significant effect on the secretion of saliva, which may be due to its ability to stimulate the muscarinic receptor. Cevimeline hydrochloride has been shown to be effective against radiation-induced xerostomia and may also be used as an adjunct therapy for chronic oral mucositis induced by cancer chemotherapy. It has been found that cevimeline induces transcriptional regulation of a number of genes, including those involved in skin cancer and chronic oral inflammation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 235.77 g/mol
• Formula: C₁₀H₁₈ClNOS
• Purity: Min. 95%