5,25r-Cholesten-3beta,26-diol

CAS: 20380-11-4

Ref. 3D-FC146890

Product Information

• Name: 5,25r-Cholesten-3beta,26-diol
• Synonyms: (25R)-26-Hydroxycholesterol, (25R)-Cholest-5-ene-3β,26-diol, (3β,25R)-Cholest-5-ene-3,26-diol, Cholest-5-ene-3,26-diol, (3β,25R)-, Cholest-5-ene-3beta,26-diol, (25R)-, Cholest-5-ene-3β,26-diol, (25R)-, cholest-5-ene-3,26-diol, (3beta,25R)-
• CAS: 20380-11-4

Description

5,25-Cholesten-3β,26-diol (5,25-DHD) is a hormone that belongs to the group of angiotensin system inhibitors. It is a potent antagonist of the angiotensin II type 1 receptor (AT1R). 5,25-DHD has been shown to inhibit hepatic steatosis and improve mitochondrial function in mice with high blood pressure. This drug also has significant cytotoxicity against tumor cells and acts as an effector protein for toll-like receptor 4 (TLR4). 5,25-DHD can bind to iron ions and transport them across the plasma membrane by binding to the ATP binding cassette transporter A1 (ABCA1). 5,25-DHD has been shown to have significant effects on brain functions such as neuronal death and growth factor β1.

• Brand: Biosynth

Chemical properties

• Molecular weight: 402.65 g/mol
• Formula: C₂₇H₄₆O₂
• Purity: Min. 95%
• Color/Form: Powder