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1-(2-Chloro-4-(4-chlorophenyl)butyl)-1H-imidazole
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1-(2-Chloro-4-(4-chlorophenyl)butyl)-1H-imidazole

CAS: 67085-12-5

Ref. 3D-FC150297

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Estimated delivery in United States, on Thursday 2 Jan 2025

Product Information

Name:
1-(2-Chloro-4-(4-chlorophenyl)butyl)-1H-imidazole
Synonyms:
  • 1H-imidazole, 1-[2-chloro-4-(4-chlorophenyl)butyl]-
Description:

1-(2-Chloro-4-(4-chlorophenyl)butyl)-1H-imidazole (1-CHLBI) is a synthetic compound that has been shown to inhibit the replication of retroviruses. It binds to the hydroxyl group on the nitrogen atom of furyl, which is part of a nucleotide in the viral dna, and prevents its incorporation into the growing chain. This inhibits rna synthesis and protein synthesis, leading to cell death and inhibition of virus production. 1-CHLBI also has antiviral activity against HIV infection. The trifluoromethyl group at position 1 prevents the metabolism by cytochrome P450 enzymes, while the nitro group at position 2 acts as an electron donor in an oxidation reaction with glutathione reductase or cytochrome P450 enzymes. 1-CHLBI also has an amide bond that can be hydrolyzed by esterases or glucuron

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
269.17 g/mol
Formula:
C13H14Cl2N2
Purity:
Min. 95%
InChI:
InChI=1S/C13H14Cl2N2/c14-12-4-1-11(2-5-12)3-6-13(15)9-17-8-7-16-10-17/h1-2,4-5,7-8,10,13H,3,6,9H2
InChI key:
InChIKey=PJMMKIMXEKRAAT-UHFFFAOYSA-N
SMILES:
Clc1ccc(CCC(Cl)Cn2ccnc2)cc1
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Hazard Info

UN Number:
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Forbidden to fly:
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