1-9H-(Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanolphosphateHemihydrate

CAS: 610309-89-2

Ref. 3D-FC150395

Product Information

• Name: 1-9H-(Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanolphosphateHemihydrate
• Synonyms: Carvedilol phosphate hemihydrate, 1-(9H-Carbozol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol phosphate hydrate (2:2:1), 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol phosphate hydrate (2:2:1), 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-, phosphate (salt), hydrate (2:2:1), 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-, phosphate, hydrate (2:2:1), Carvedilol Phosphate, Carvedilol dihydrogen phosphate hemihydrate, Coreg CR, Skf 105517D

Description

The chemical stability of 1-9H-(carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanolphosphate hemihydrate (1) was studied at 25°C and 40°C in phosphate buffer, pH 6.5, for 1 month. The compound is stable in the presence of water vapor and epidermal growth factor (EGF). The stability of 1 was also tested by reacting it with various solvents and excipients to determine the compatibility of 1 with other compounds. Carvedilol phosphate was found to be compatible with 1 and can be used as an excipient. A model system was designed to study the interaction of a fluorescent dye (DAPI) with 1, which showed that no fluorescence quenching occurred at concentrations up to 10 μM. A fluorescence detector was used to measure the emission spectrum of DAPI in the presence of

• Brand: Biosynth

Chemical properties

• Molecular weight: 522.48 g/mol
• Formula: C₂₄H₃₁N₂O₉P
• Purity: Min. 95%