Product Information
- 2-Chloro-6-Iodopyridin-3-Ol
- 3-Hydroxy-6-chloro-2-iodopyridine
- 3-Pyridinol, 6-chloro-2-iodo-
- 6-Chloro-2-iodo-3-pyridinol
6-Chloro-2-iodopyridin-3-ol is a potent and selective inhibitor of indoleamine 2,3 dioxygenase (IDO), an enzyme that catalyzes the first step in the degradation of tryptophan. 6CIOD inhibits IDO activity in vitro with a Ki value of 0.0005 μM. This compound has been shown to have anti-inflammatory effects in vivo, reducing adjuvant arthritis in rats when given prophylactically or therapeutically at doses of 1 mg/kg.
Chemical properties
Technical inquiry about: 3D-FC154528 6-Chloro-2-iodopyridin-3-ol
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