2-Chlorobenzyl isocyanate

CAS: 55204-93-8

Ref. 3D-FC157986

Product Information

• Name: 2-Chlorobenzyl isocyanate
• Synonyms: Benzene, 1-Chloro-2-(Isocyanatomethyl)-

Description

2-Chlorobenzyl isocyanate (2-CBI) is a potent inhibitor of tumor necrosis factor (TNF)-α. It interacts with the TNF receptor and prevents it from binding to the TNF ligand, thereby preventing the activation of the TNF signaling pathway. 2-CBI has also been shown to inhibit intramolecular hydrogen bonding in lipopolysaccharide, which prevents its binding to cell receptors. This drug may be useful in the treatment of osteoarthritis and other diseases that are associated with inflammation.

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2-Chlorobenzyl isocyanate inhibits tumor necrosis factor (TNF)-α by interacting with its receptor and preventing it from binding to the TNF ligand, thereby preventing activation of the TNF signaling pathway. It also inhibits intramolecular hydrogen bonding in lipopolysaccharide, which prevents it from binding to cell

• Brand: Biosynth

Chemical properties

• Molecular weight: 167.59 g/mol
• Formula: C₈H₆ClNO
• Purity: Min. 95%
• InChI: InChI=1S/C8H6ClNO/c9-8-4-2-1-3-7(8)5-10-6-11/h1-4H,5H2
• InChI key: InChIKey=IBRWLEYNCGRJLX-UHFFFAOYSA-N
• SMILES: O=C=NCc1ccccc1Cl