Product Information
- 1-Benzoyl-3-chloropropane
- 1-Butanone, 4-chloro-1-phenyl-
- 3-Benzoylpropyl chloride
- 3-Chloropropyl phenyl ketone
- 4-Chloro-1-phenyl-1-butanone
- 4-Chlorobutylphenone
- 4-Chlorobutyrophenone
- Butyrophenone, 4-chloro-
- NSC 76579
- γ-Chlorobutyrophenone
- See more synonyms
4-Chloro-1-phenyl-butan-1-one is a chlorinated aromatic compound that is used to synthesize phenylacetaldehyde. This compound can be prepared by a Friedel-Crafts reaction with chlorobenzene and aluminum chloride. The reaction requires palladium catalysis, which lowers the activation energy of the reaction and increases the yield. 4-Chloro-1-phenyl-butan-1-one is an important precursor for many pharmaceuticals, such as anesthetics, antibiotics, and antidepressants. It is also used to synthesize other compounds, such as aziridines and cyclic amines.
4-Chloro-1-phenyl butan 1 one has a high yield in this reaction because it does not require the use of solvents or catalysts. The reaction is carried out at room temperature in anhydrous conditions. The product contains unsaturation due to the presence of two phen
