6-Chloro-3-hydroxypyrazine-2-carboxamide

CAS: 259793-90-3

Ref. 3D-FC177945

Product Information

• Name: 6-Chloro-3-hydroxypyrazine-2-carboxamide
• Synonyms: Favipiravir Impurity 3
• CAS: 259793-90-3

Description

6-Chloro-3-hydroxypyrazine-2-carboxamide is a small molecule antiviral agent that has shown promise in research for the treatment of filovirus infections, such as Ebola virus. This drug has a pharmacokinetic profile that is characterized by high oral bioavailability and low clearance. It also has a good safety profile in animal studies, with no adverse effects at doses up to 3,000 mg/kg. 6-Chloro-3-hydroxypyrazine-2-carboxamide inhibits the replication of Ebola virus in cell culture and shows promising activity against both Marburg and Sudan viruses. The drug has been shown to be effective in nonhuman primates when used prophylactically or therapeutically.

• Brand: Biosynth

Chemical properties

• Molecular weight: 173.56 g/mol
• Formula: C₅H₄ClN₃O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C5H4ClN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)
• InChI key: InChIKey=XERRFWUVFFKJNT-UHFFFAOYSA-N
• SMILES: NC(=O)c1nc(Cl)c[nH]c1=O