Chlorcyclizine hydrochloride

CAS: 14362-31-3

Ref. 3D-FC178661

Product Information

• Name: Chlorcyclizine hydrochloride
• Synonyms: 1-(P-Chloro-Alpha-Phenylbenzyl)-4-Methyl-Piperazinhydrochloride, 1-(P-Chloro-Alpha-Phenylbenzyl)-4-Methylpiperazinehydrochloride, 1-(P-Chlorobenzhydryl)-4-Methylpiperazinehydrochloride, 1-(p-Chloro-alpha-phenylbenzyl)-4-methylpiperazine hydrochloride, 1-(p-Chloro-alpha-phenylbenzyl)-4-methylpiperazine monohydrochloride, 1-[(4-Chlorophenyl)(Phenyl)Methyl]-4-Methylpiperazine, 1-[(4-Chlorophenyl)(Phenyl)Methyl]-4-Methylpiperazine Hydrochloride (1:1), 1-[(4-Chlorophenyl)Phenyl-Methyl]-4-Methylpiperazine Hydrochloride, Chlorcyclizine HCL, Chlorcyclizine chloride, Chlorcyclizine monohydrochloride, Chlorcycliziniumchloride, Di-Paralene, Eramide, Histantin, Mantadil, NSC 169496, Perazil, Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-methyl-, hydrochloride, Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-methyl-, monohydrochloride, Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-methyl-, hydrochloride, Piperazine, 1-(p-chloro-α-phenylbenzyl)-4-methyl-, monohydrochloride, Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-methyl-, hydrochloride (1:1), Unii-Npb7A7874U
• CAS: 14362-31-3

Description

Chlorcyclizine hydrochloride is a potent inhibitor of the growth factor-β1 receptor. It also has antimicrobial activity and can be used as an antiseptic, especially for the treatment of eye infections. Chlorcyclizine hydrochloride is a potent inducer of toll-like receptor 4 (TLR4) which is responsible for innate immunity against bacteria and fungi. This drug also inhibits propranolol hydrochloride binding to the β2-adrenergic receptor, which may lead to cardiotoxicity in some patients. The compound has shown significant cytotoxicity on liver cells in vitro, but not on other cell lines; this toxicity may be due to its ability to react with iodides in solution, forming reactive intermediates that cause cellular damage.

• Brand: Biosynth

Chemical properties

• Molecular weight: 337.29 g/mol
• Formula: C₁₈H₂₂Cl₂N₂
• Purity: Min. 95 Area-%
• Color/Form: Powder