Captopril EP Impurity J

CAS: 64838-55-7

Ref. 3D-FC179764

Product Information

• Name: Captopril EP Impurity J
• Synonyms: (2S)-1-[(2S)-3-(acetylsulfanyl)-2-methylpropanoyl]pyrrolidine-2-carboxylate, (S,S)-1-(<span class="text-smallcaps">D</smallcap>-3-Acetylthio-2-methylpropanoyl)-<smallcap>L</span>-proline, 1-[(2S)-3-(Acetylsulfanyl)-2-methylpropanoyl]-L-proline, 1-[(2S)-3-(Acetylthio)-2-methyl-1-oxopropyl]-<span class="text-smallcaps">L</span>-proline, 1-[(2S)-3-(Acetylthio)-2-methyl-1-oxopropyl]-L-proline, 1-[3-(Acetylsulfanyl)-2-Methylpropanoyl]Proline, 1-[3-(acetylsulfanyl)-2-methylpropanoyl]-L-proline, <span class="text-smallcaps">L</span>-Proline, 1-[(2S)-3-(acetylthio)-2-methyl-1-oxopropyl]-, <span class="text-smallcaps">L</span>-Proline, 1-[3-(acetylthio)-2-methyl-1-oxopropyl]-, (S)-, Du 1163, L-proline, 1-[(2S)-3-(acetylthio)-2-methyl-1-oxopropyl]-, S-Acetylcaptopril

Description

Captopril EP Impurity J is an impurity of captopril that has been shown to be pharmacologically active. Captopril EP Impurity J binds to angiotensin receptors and is a potent inhibitor of the renin-angiotensin system. It also has selective effects on tissues such as the choroid and striatum, where it inhibits formation of angiotensin II. Captopril EP Impurity J is metabolized by hepatic enzymes, leading to the production of thiorphan, which has similar pharmacologic properties but lacks selectivity for tissues. Captopril EP Impurity J is reversible in rat tissues and may have a role in the development of hypertension.

• Brand: Biosynth

Chemical properties

• Molecular weight: 259.32 g/mol
• Formula: C₁₁H₁₇NO₄S
• Purity: 90%Min