Carbazeran

CAS: 70724-25-3

Ref. 3D-FC19687

Product Information

• Name: Carbazeran
• Synonyms: N-Ethylcarbamic acid 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl esterEthylcarbamic acid 1-(6,7-dimethoxy-1-phthalazinyl)-4-pipe ridinyl esterUK 31557, 1-(6,7-Dimethoxyphthalazin-1-yl)piperidin-4-yl ethylcarbamate, 70724-25-3, Carbamic acid, ethyl-, 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl ester, Ethylcarbamic Acid 1-(6,7-Dimethoxy-1-phthalazinyl)-4-piperidinyl Ester, Uk 31557, carbamic acid, N-ethyl-, 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl ester

Description

Carbazeran is a novel pharmacological agent that is being developed for the treatment of bowel disease. It inhibits the enzyme dipeptidyl peptidase-4 (DPP-4) and has been shown to have beneficial effects in vitro on human cells and in vivo models of heart failure. DPP-4 is responsible for breaking down the hormone glucagon-like peptide 1 (GLP-1), which has been shown to have beneficial effects on inflammatory bowel disease. Carbazeran binds to DPP-4, thereby inhibiting its activity, and prevents the breakdown of GLP-1. This leads to an increase in GLP-1 levels and an improvement in inflammatory bowel disease symptoms.

• Brand: Biosynth

Chemical properties

• Molecular weight: 360.41 g/mol
• Formula: C₁₈H₂₄N₄O₄
• Purity: Min. 95%
• InChI: InChI=1S/C18H24N4O4/c1-4-19-18(23)26-13-5-7-22(8-6-13)17-14-10-16(25-3)15(24-2)9-12(14)11-20-21-17/h9-11,13H,4-8H2,1-3H3,(H,19,23)
• InChI key: InChIKey=QJGVXJYGDBSPSJ-UHFFFAOYSA-N
• SMILES: CCNC(=O)OC1CCN(c2nncc3cc(OC)c(OC)cc23)CC1