trans-Carboxy glimepiride
CAS: 127554-90-9
Ref. 3D-FC19733
| 1mg | To inquire | ||
| 2mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire |
Product Information
- trans-4-[[[[[4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulfonyl]amino]carbonyl]amino]cyc lohexanecarboxylic acid
Trans-carboxy glimepiride is a prodrug of the sulfonylurea class and is metabolized in vivo to its active form, glimepiride. Trans-carboxy glimepiride has been shown to have a high affinity for the catalytic site of the enzyme dipeptidyl peptidase IV (DPP-IV), which is responsible for the degradation of many peptides that regulate blood sugar levels. This interaction leads to inhibition of DPP-IV, which prevents inactivation of glucagon and other peptides that regulate blood sugar levels. Trans-carboxy glimepiride also interacts with other enzymes involved in gluconeogenesis, such as phosphoenolpyruvate carboxykinase (PEPCK) and glucose 6-phosphatase (G6Pase).
Chemical properties
Technical inquiry about: 3D-FC19733 trans-Carboxy glimepiride
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