Cbz-cyclohexyl-L-glycine

CAS: 69901-75-3

Ref. 3D-FC19841

Product Information

• Name: Cbz-cyclohexyl-L-glycine
• Synonyms: (a-S)-a-[[(Phenylmethoxy)carbonyl]amino]cyclohexaneacetic acid(S)-a-[[(phenylmethoxy)carbonyl]amino]cyclohexaneacetic acid, (2S)-2-Cyclohexyl-2-(phenylmethoxycarbonylamino)acetic acid, (2S)-{[(benzyloxy)carbonyl]amino}(cyclohexyl)ethanoic acid, (S)-2-(((Benzyloxy)carbonyl)amino)-2-cyclohexylaceticacid, (αS)-α-[[(Phenylmethoxy)carbonyl]amino]cyclohexaneacetic acid, Cbz-Chg-Oh, Cbz-Cyclohexyl-L-Glycine, Cyclohexaneacetic acid, α-[[(phenylmethoxy)carbonyl]amino]-, (S)-, Cyclohexaneacetic acid, α-[[(phenylmethoxy)carbonyl]amino]-, (αS)-, N-[(benzyloxy)carbonyl]-N-cyclohexylglycine, Z-Chg-Oh
• CAS: 69901-75-3

Description

Cbz-cyclohexyl-L-glycine is an aminoalcohol that is used as a process development and optimization tool. It is a substrate for proteases, which cleave the peptide bond at the C-terminal end of the molecule. Telaprevir (TPV) is an inhibitor of this enzyme, which inhibits the activity of various viruses, including hepatitis C virus (HCV). TPV is currently undergoing clinical trials for HCV treatment. The TPV molecule can be synthesized by attaching cbz-cyclohexyl-L-glycine to TPV's amide group. This product has shown potential as an antiviral agent against HCV and other viruses.

• Brand: Biosynth

Chemical properties

• Molecular weight: 291.34 g/mol
• Formula: C₁₆H₂₁NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C16H21NO4/c18-15(19)14(13-9-5-2-6-10-13)17-16(20)21-11-12-7-3-1-4-8-12/h1,3-4,7-8,13-14H,2,5-6,9-11H2,(H,17,20)(H,18,19)/t14-/m0/s1
• InChI key: InChIKey=CUSYTUPJAYLNFQ-AWEZNQCLSA-N
• SMILES: O=C(N[C@H](C(=O)O)C1CCCCC1)OCc1ccccc1