7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid

CAS: 100361-18-0

Ref. 3D-FC19978

Product Information

• Name: 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid
• Synonyms: 3-Carboxy-7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro[1,8]naphthyridine, 1,8-Naphthyridine-3-carboxylic acid, 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, 1-Cyclopropyl-6-Fluoro-7-Chloride-4-Oxo-1,4-Dihydro-1,8-Napthyridine-3-Carboxylie acid, 1-Cyclopropyl-6-Fluoro-7-Chloro-4-Oxo-1,4-Dihydro-1,8-, 1-Cyclopropyl-6-fluoro-7-chloride-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid, 1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylicacid, 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid, 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylicacid, Ethyl 1-Cyclopropyl-7-Chloro-6-Fluoro-1,4-Dihydro-4-Oxo-1,8-Naphthylridine Carboxylate, Ethyl 1-cyclopropyl-7-Chloro-6-fluoro-1,4-dihydro-4-oxo-1,8-napthyridine Carboxylate, Ethyl 7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylate, Ethyl1-Cyclopropyl-6-Fluoro-7-Chloro-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylate, Naphthyridine-3-Carboxylic acid, 7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydro-1,8-Naphthyridin-3-Carboxylic Acid, 1-Cyclopropyl-6-Fluoro-7-Chloro-4-Oxo-1,4-Dihydro-1,8-, Naphthyridine-3-Carboxylic acid

Description

7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-[1,8]naphthyridine-3-carboxylic acid is a synthetic fluorinated naphthyridine antibiotic and a new member of the fluoroquinolones. It has a broad spectrum of bactericidal activity against Gram negative and Gram positive bacteria. 7C6FNC was validated by statistical analysis, chromatographic separation, radiation, hydrogen peroxide and bioassay. This compound is synthesized by mesylation of 2-(4′chlorobiphenyl)-3′(2′chlorophenyl)propanoic acid with 4-(dimethylamino)pyridine in acetonitrile at room temperature followed by hydrolysis with potassium hydroxide in methanol to produce 7C6FNC as a white solid. The reaction vessel was prepared from glassware that had been washed with water then dried in

• Brand: Biosynth

Chemical properties

• Molecular weight: 282.65 g/mol
• Formula: C₁₂H₈ClFN₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C12H8ClFN2O3/c13-10-8(14)3-6-9(17)7(12(18)19)4-16(5-1-2-5)11(6)15-10/h3-5H,1-2H2,(H,18,19)
• InChI key: InChIKey=OXNZWNNMJBOZQO-UHFFFAOYSA-N
• SMILES: O=C(O)c1cn(C2CC2)c2nc(Cl)c(F)cc2c1=O