7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

CAS: 68077-26-9

Ref. 3D-FC19979

Product Information

• Name: 7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
• Synonyms: 7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid1-Ethyl-1,4-dihydro-4-oxo-6-fluoro-7-chloro-3-quinolinecarbox ylic acid7-Chloro-1,4-dihydro-1-ethyl-6-fluoro-4-oxo-3-quinolinecarboxylic acid, 1-Ethyl-1,4-dihydro-4-oxo-6-fluoro-7-chloro-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-7-chloro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 1-Ethyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid, 1-Ethyl-7-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 1-Ethyl-7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 3-Quinolinecarboxylic Acid, 7-Chloro-1-Ethyl-6-Fluoro-1,4-Dihydro-4-Oxo-, 7-Chloro-1,4-dihydro-1-ethyl-6-fluoro-4-oxo-3-quinolinecarboxylic acid, 7-Chloro-1-Ethyl-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate, 7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, 7-Chloro-1-ethyl-6-fluoroquinolin-4-one-3-carboxylic acid, Cga 78039, M 193324

Description

7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid is a carboxyl group with a 3-chloroperoxybenzoic acid. It has been shown to be an effective antimicrobial agent against gram positive and gram negative bacteria, as well as fungi. 7CQCA is not active against mycoplasma or spirochetes. This compound is synthesized in the presence of 1% hydrochloric acid (HCl) and 10% trifluoride. The synthesis proceeds through the following steps: (1) chlorination of ethyl acetate (EtOAc), (2) dehydrogenation of the resultant 7CQCA, (3) hydrolysis of the resultant carboxylic acid, and (4) acetone reduction of the resultant quinoline ring to produce 7CQCA.

• Brand: Biosynth

Chemical properties

• Molecular weight: 269.66 g/mol
• Formula: C₁₂H₉ClFNO₃
• Purity: Min. 95%
• InChI: InChI=1S/C12H9ClFNO3/c1-2-15-5-7(12(17)18)11(16)6-3-9(14)8(13)4-10(6)15/h3-5H,2H2,1H3,(H,17,18)
• InChI key: InChIKey=WNNSMMJBBOPPOT-UHFFFAOYSA-N
• SMILES: CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)cc21