1-Chloro-4-(4-pyridinylmethyl)phthalazine

CAS: 101094-85-3

Ref. 3D-FC20074

Product Information

• Name: 1-Chloro-4-(4-pyridinylmethyl)phthalazine
• Synonyms: 1-Chloro-4-[(4-pyridyl)methyl]phthalazine, 1-Chloro-4-(4-pyridylmethyl)phthalazine, 1-Chloro-4-(4-Pyridinylmethyl)Phthalazine, 95+%, 1-Chloro-4-(Pyridin-4-Ylmethyl)Phthalazine

Description

1-Chloro-4-(4-pyridinylmethyl)phthalazine is a chemical compound that inhibits the p38 kinase pathway in cells. It binds to the constant region of the enzyme and prevents it from phosphorylating its substrate, thereby blocking signal transduction. This can lead to the inhibition of hyperproliferative diseases such as cancer. 1-Chloro-4-(4-pyridinylmethyl)phthalazine has been shown to inhibit tumor growth and induce cell death in a variety of human cancer cell lines by inhibiting the p38 kinase pathway.

• Brand: Biosynth

Chemical properties

• Molecular weight: 255.7 g/mol
• Formula: C₁₄H₁₀ClN₃
• Purity: Min. 95%
• InChI: InChI=1S/C14H10ClN3/c15-14-12-4-2-1-3-11(12)13(17-18-14)9-10-5-7-16-8-6-10/h1-8H,9H2
• InChI key: InChIKey=LVSFOJFCLFTXTO-UHFFFAOYSA-N
• SMILES: Clc1nnc(Cc2ccncc2)c2ccccc12