9-(2-Chloro-ethyl)-9H-purin-6-ylamine
CAS: 19255-48-2
Ref. 3D-FC20234
| 1g | Discontinued | ||
| 2g | Discontinued | ||
| 5g | Discontinued | ||
| 10g | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
9-(2-Chloro-ethyl)-9H-purin-6-ylamine
Synonyms:
- 9-(2-Chloroethyl)adenineNSC 50715
- 9-(2-chloroethyl)-9H-purin-6-amine
Description:
9-(2-Chloro-ethyl)-9H-purin-6-ylamine is a nucleotide analog. It forms hydrogen bonds with DNA bases, which may be due to the chloride ion acting as an electron acceptor. This interaction leads to cross-linking and yields low molecular weight analogs in the presence of diallylamine. 9-(2-Chloro-ethyl)-9H-purin-6-ylamine has also been shown to form hydrophobic interactions with the phosphate groups in DNA. This synthetic drug is often used in cancer chemotherapy and can be synthesized from 2,4,6-trichloropyrimidine and 1-(2 chloroethyl)pyridinium iodide.
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
197.62 g/mol
Formula:
C7H8ClN5
Purity:
Min. 95%
InChI:
InChI=1S/C7H8ClN5/c8-1-2-13-4-12-5-6(9)10-3-11-7(5)13/h3-4H,1-2H2,(H2,9,10,11)
InChI key:
InChIKey=KXIXGDZXYORBNW-UHFFFAOYSA-N
SMILES:
Nc1ncnc2c1ncn2CCCl
MDL:
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