1-(4-Chlorophenyl)cyclobutane carbonitrile

CAS: 28049-61-8

Ref. 3D-FC20340

Product Information

• Name: 1-(4-Chlorophenyl)cyclobutane carbonitrile
• Synonyms: 1-(4-Chlorophenyl)cyclobutanecarbonitrile1-(p-Chlorophenyl)cyclobutanecarbonitrileNSC 154613, 1-(4-Chlorophenyl)-1-Cyclobutanecarbonitrile, 1-(4-Chlorophenyl)cyclobutane-1-carbonitrile, 1-(p-Chlorophenyl)cyclobutanecarbonitrile, Cyclobutanecarbonitrile, 1-(4-chlorophenyl)-, Cyclobutanecarbonitrile, 1-(p-chlorophenyl)-, NSC 154613, 1-(4-Chlorophenyl)cyclobutanecarbonitrile

Description

1-(4-Chlorophenyl)cyclobutane carbonitrile is an inhibitor of monoamine oxidase B (MAO-B) and dopamine reuptake. It has been used as a potential treatment for human immunodeficiency virus (HIV). The binding of 1-(4-Chlorophenyl)cyclobutane carbonitrile to MAO-B was studied in kinetic data and hybridization studies. The results showed that the drug binds to the enzyme with high affinity, and that it has a higher affinity for MAO-B than for the other two isoforms of this enzyme. In addition, 1-(4-Chlorophenyl)cyclobutane carbonitrile is a bifunctional molecule, which means it can bind to two different enzymes at the same time. The drug also inhibits dopamine reuptake by blocking dopamine transporters on nerve cells, which increases dopamine levels in the brain. This activity makes it a potential

• Brand: Biosynth

Chemical properties

• Molecular weight: 191.66 g/mol
• Formula: C₁₁H₁₀ClN
• Purity: Min. 95%