Clinofibrate

CAS: 30299-08-2

Ref. 3D-FC20487

Product Information

• Name: Clinofibrate
• Synonyms: 1,1-Bis[4'-(1''-carboxy-1''-methylpropoxy)phenyl]cyclohexane2,2'-[Cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methyl-butanoic acidL ipoclin, 1,1-Bis[4'-(1''-carboxy-1''-methylpropoxy)phenyl]cyclohexane, 2,2'-(Cyclohexylidenebis(4,1-Phenyleneoxy))Bis(2-Methyl)-Butanoic Acid, 2,2'-[Cyclohexane-1,1-Diylbis(Benzene-4,1-Diyloxy)]Bis(2-Methylbutanoic Acid), 2,2’-(4,4’-Cyclohexylidenediphenoxy)-2,2’-Dimethyldibutyricacid, 2,2’-Cyclohexane-1,1-Diylbis(P-Phenyleneoxy)Bis(2-Methylbutyricacid), 2,2’-Cyclohexane-1,1-Diylbis(P-Phenyleneoxy)Bis-(2-Methyl-Butyricaci, 2,2′-[Cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methylbutanoic acid], Butanoic acid, 2,2′-[cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methyl-, Clinofibrate(Forr&Donly), Lipoclin, S 8527

Description

Clinofibrate is a hypolipidemic agent that is used to lower serum cholesterol levels. It is a prodrug that is converted to its active form, clofibrate, in the liver. Clinofibrate inhibits hydroxylation of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) by inhibiting the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase, which is involved in the synthesis of cholesterol. Clinofibrate also has been shown to reduce atherosclerotic plaque formation in animal models and has been shown to have pharmacokinetic properties similar to those of other hypolipidemic agents.

• Brand: Biosynth

Chemical properties

• Molecular weight: 468.58 g/mol
• Formula: C₂₈H₃₆O₆
• Purity: Min. 95%