Clodronic acid disodium salt

CAS: 22560-50-5

Ref. 3D-FC20495

Product Information

• Name: Clodronic acid disodium salt
• Synonyms: (Dichloromethylene)bisphosphonic acid disodium saltClodronate disodiumBonefos, (Dichloromethylene)diphosphonate disodium, Bm 06011, Bonefos, Clasteon, Clodronate, Clodronate disodium, Clodronate disodium salt, Clodronate sodium, Clodronic Acid Disodium Salt, DClMDP, Dichloromethylenebisphosphonic acid disodium salt, Dichloromethylenediphosphonic Acid Disodium Salt, Difoafonal, Diphosfonal, Disodium (Dichloromethanediyl)Bis[Hydrogen (Phosphonate)], Disodium (dichloromethane)diphosphonate, Disodium (dichloromethylene)bisphosphonate, Disodium (dichloromethylene)diphosphonate, Disodium clodronate, Disodium dichloromethylenebis(hydrogenphosphonate) tetrahydrate, Lodronate, Loron, Mebonat, Ossiten, Ostac, Phosphonic acid, (dichloromethylene)bis-, disodium salt, Phosphonic acid, (dichloromethylene)di-, disodium salt, Phosphonic acid, P,P′-(dichloromethylene)bis-, sodium salt (1:2), Sodium (dichloromethylene)diphosphonate, Sodium clodronate
• CAS: 22560-50-5

Description

Clodronic acid disodium salt is a drug that can be used as a treatment for bowel disease. It binds to the chemoattractant protein and inhibits the activation of toll-like receptor 4, which is involved in inflammatory reactions. Clodronic acid also has an effect on polymorphonuclear leucocytes, inhibiting the production of cytokines and other inflammatory mediators. Clodronic acid has been shown to reduce neuronal death in experimental models and inhibit mitochondrial membrane potential in leukemic mice. The drug acts by binding to basic proteins in bone cells, preventing the release of calcium from bone stores into the blood stream. The monosodium salt form is more soluble than clodronate, which is a disodium salt.

• Brand: Biosynth

Chemical properties

• Molecular weight: 288.86 g/mol
• Formula: CH₂Cl₂Na₂O₆P₂
• Purity: Min. 95%
• Color/Form: White Powder