Product Information
- 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin ACyclosporin A metabolite 17Cyclosporin metabo lite 17
Cyclosporin A is a cyclic nonapeptide that is an immunosuppressant drug. Cyclosporin A inhibits the production of interleukin-2 (IL-2) and other cytokines by human lymphocytes, and has been shown to suppress graft-versus-host disease in rat hepatocyte cultures. Cyclosporin A is a potent inhibitor of the enzyme cyclooxygenase, which converts arachidonic acid to prostaglandins such as PGE2. Cyclosporine A also binds to specific antibodies, or immunoglobulins, that are found in the blood plasma. This binding prevents the cells from reacting with each other and initiating a chain reaction. Cyclosporin AM 1 is a dry extract of cyclosporine prepared by spray drying that maintains its chemical stability and its pharmaceutical activity over time. It can be used as a coating for tablets or capsules or incorporated into the chemical composition of other products
Chemical properties
Technical inquiry about: 3D-FC20753 Cyclosporin AM 1
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