Calpain inhibitor I

CAS: 110044-82-1

Ref. 3D-FC29614

Product Information

• Name: Calpain inhibitor I
• Synonyms: <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-(1-formylpentyl)-, (S)-, <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[(1S)-1-formylpentyl]-, ALLNal, ALLnL, CI-1 (peptide), Calp I, Mg 101, N-Ac-Leu-Leu-Norleucinal, N-Acetyl-<span class="text-smallcaps">L</smallcap>-leucinyl-<smallcap>L</smallcap>-leucinyl-<smallcap>L</span>-norleucinal, N-Acetyl-<span class="text-smallcaps">L</smallcap>-leucyl-N-[(1S)-1-formylpentyl]-<smallcap>L</span>-leucinamide, N-Acetyl-L-Leucyl-L-Leucyl-L-Norleucinal, N-Acetyl-Leu-Leu-Nle-Cho, N-Acetyl-Leu-Leu-Norleucinal, N-acetyl-L-leucyl-N-[(2S)-1-oxohexan-2-yl]-L-leucinamide, N-acetyl-L-leucyl-N-[(2S)-1-oxohexan-2-yl]leucinamide, N-acetylleucyl-N-(1-oxohexan-2-yl)leucinamide, L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formylpentyl]-, L-Leucinamide, N-acetyl-L-leucyl-N-(1-formylpentyl)-, (S)-, N-Acetyl-L-leucyl-N-[(1S)-1-formylpentyl]-L-leucinamide

Description

Calpain inhibitor I is a small molecule that inhibits calpains by binding to the catalytic domain. It has been shown to have anti-inflammatory properties and may be useful in treating bowel diseases, such as Crohn's disease, and other inflammatory conditions. Calpain inhibitor I has also been shown to inhibit tumor growth in mice with subcutaneous tumors. In addition, it may inhibit neuronal death and angiogenesis in the brain. This drug binds to calpains and inhibits their enzymatic activity, which prevents apoptosis of neurons.

• Brand: Biosynth

Chemical properties

• Molecular weight: 383.53 g/mol
• Formula: C₂₀H₃₇N₃O₄
• Purity: Min. 95%
• Color/Form: White Powder