2-[4-[(7-Chloroquinolin-4-yl)amino]pentylamino]ethanol

CAS: 4298-15-1

Ref. 3D-FC29937

Product Information

• Name: 2-[4-[(7-Chloroquinolin-4-yl)amino]pentylamino]ethanol
• Synonyms: Cletoquine, 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)amino)ethanol, 2-({4-[(7-Chloroquinolin-4-Yl)Amino]Pentyl}Amino)Ethanol, 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]amino]ethanol, Cletochina, Cletochina [DCIT], Cletoquina, Cletoquina [INN-Spanish], Cletoquine [INN:BAN], Cletoquinum, Cletoquinum [INN-Latin], Desethylhydroxychloroquine, Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]amino]-, Ethanol, 2-[[4-[(7-chloro-4-quinolyl)amino]pentyl]amino]-, Unii-83Cvd213Tu

Description

2-[4-[(7-Chloroquinolin-4-yl)amino]pentylamino]ethanol is an α1-acid glycoprotein (AAG) inhibitor. It has a matrix effect on analytical methods and can be used to prepare samples for analysis. 2-[4-[(7-Chloroquinolin-4-yl)amino]pentylamino]ethanol inhibits autophagy, which is the process of degradation of cellular components by lysosomes. It has been shown to have disease activity against autoimmune diseases and HIV infection. Animal studies have shown that 2-[4-[(7-Chloroquinolin-4-yl)amino]pentylamino]ethanol can reduce inflammation in rat liver microsomes and has antiarthritic effects in rats with adjuvant arthritis. This drug also has dose group effects on serum creatinine, urea nitrogen, and uric acid levels.

• Brand: Biosynth

Chemical properties

• Molecular weight: 307.82 g/mol
• Formula: C₁₆H₂₂ClN₃O
• Purity: 85%Nmr
• Color/Form: White To Beige To Light Brown Solid
• InChI: InChI=1S/C16H22ClN3O/c1-12(3-2-7-18-9-10-21)20-15-6-8-19-16-11-13(17)4-5-14(15)16/h4-6,8,11-12,18,21H,2-3,7,9-10H2,1H3,(H,19,20)
• InChI key: InChIKey=XFICNUNWUREFDP-UHFFFAOYSA-N
• SMILES: CC(CCCNCCO)Nc1ccnc2cc(Cl)ccc12