5-(Chlorosulfonyl)-2-fluorobenzoic acid

CAS: 37098-75-2

Ref. 3D-FC33418

Product Information

• Name: 5-(Chlorosulfonyl)-2-fluorobenzoic acid
• Synonyms: Benzoic Acid, 5-(Chlorosulfonyl)-2-Fluoro-

Description

5-(Chlorosulfonyl)-2-fluorobenzoic acid is a halogenated aromatic compound that functions as a nucleophile. It is used in the synthesis of sulfonamides and other compounds. 5-(Chlorosulfonyl)-2-fluorobenzoic acid has been shown to react with amines, thiols, and alcohols via intramolecular nucleophilic displacement. The reaction proceeds by an initial electrophilic attack by the chlorine on the carbon atom adjacent to the benzene ring, followed by a nucleophilic substitution at the ortho position. This compound can also be used to form sulfonamides by reacting with amines or thiols in the presence of sulfur dioxide.

• Brand: Biosynth

Chemical properties

• Molecular weight: 238.62 g/mol
• Formula: C₇H₄ClFO₄S
• Purity: Min. 95%
• InChI: InChI=1S/C7H4ClFO4S/c8-14(12,13)4-1-2-6(9)5(3-4)7(10)11/h1-3H,(H,10,11)
• InChI key: InChIKey=CISMZCVQNVNWJW-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(S(=O)(=O)Cl)ccc1F