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c3-Chloro-4-methylpyridine
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c3-Chloro-4-methylpyridine

CAS: 72093-04-0

Ref. 3D-FC33804

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Estimated delivery in United States, on Friday 22 Nov 2024

Product Information

Name:
c3-Chloro-4-methylpyridine
Synonyms:
  • 3-Chloro-4-picoline
  • 4-Picoline, 3-chloro-
  • Pyridine, 3-Chloro-4-Methyl-
Description:

C3-Chloro-4-methylpyridine is an intermediate in the synthesis of tofacitinib, a drug used to treat rheumatoid arthritis. C3-Chloro-4-methylpyridine is prepared by asymmetric hydrogenation of 3,5-dichloro-2,6-dimethylaniline. This process proceeds through an acylation step followed by an asymmetric hydrogenation. The reaction mixture consists of the desired product and a significant amount of 3,5 dichloropyridine. The desired product can be isolated from this mixture using column chromatography or recrystallization.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
127.57 g/mol
Formula:
C6H6ClN
Purity:
Min. 95%
MDL:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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