5-Chloro-2-cyano-3-nitropyridine
CAS: 181123-11-5
Ref. 3D-FC37947
| 5g | To inquire | ||
| 10g | To inquire | ||
| 25g | To inquire | ||
| 50g | To inquire | ||
| 100g | To inquire |
Product Information
- 2-Pyridinecarbonitrile, 5-Chloro-3-Nitro-
- 5-Chloro-3-nitro-2-pyridinecarbonitrile
- 5-Chloro-3-nitropyridine-2-carbonitrile
5-Chloro-2-cyano-3-nitropyridine is an antagonist of the glycine site on the N-methyl-D-aspartate receptor (NMDAR), which is a type of glutamate receptor. It has been shown to be a potent antagonist in rat cortical membranes and cloned rat brain cells, but not in Xenopus oocytes. 5-Chloro-2-cyano-3-nitropyridine has been shown to block NMDA receptors by binding to the glycine site, which blocks the receptor from being activated by glycine or D -serine. This prevents excitatory signals from being transmitted across the synapse, inhibiting neuronal activity.
Chemical properties
Technical inquiry about: 3D-FC37947 5-Chloro-2-cyano-3-nitropyridine
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