3-Chloro-4-fluorobenzoic acid

CAS: 403-16-7

Ref. 3D-FC38071

Product Information

• Name: 3-Chloro-4-fluorobenzoic acid
• Synonyms: 3-Chloro-4-Fluorobenzoate, 4-Fluoro-3-Chlorobenzoicacid, 5-Chloro-4-difluorobenzoic acid, Benzoic acid, 3-chloro-4-fluoro-, Qvr Cg Df
• CAS: 403-16-7

Description

3-Chloro-4-fluorobenzoic acid is a prodrug that is converted to fluvoxamine maleate, its active form, by esterases. It is an inhibitor of the enzyme nitric oxide synthase and is used in the treatment of cancer. 3-Chloro-4-fluorobenzoic acid has been shown to inhibit cellular growth and proliferation in cancer cells. The molecular modeling study showed that 3-chloro-4-fluorobenzoic acid binds to the kinesin motor domain in a manner similar to fluvoxamine maleate but has a lower inhibitory potency than fluvoxamine maleate. Nonetheless, it was found that 3-chloro-4-fluorobenzoic acid could be used as a prodrug for fluvoxamine maleate.

• Brand: Biosynth

Chemical properties

• Molecular weight: 174.56 g/mol
• Formula: C₇H₄ClFO₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C7H4ClFO2/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3H,(H,10,11)
• InChI key: InChIKey=PKTSBFXIHLYGEY-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccc(F)c(Cl)c1