Cefetamet

CAS: 65052-63-3

Ref. 3D-FC40875

Product Information

• Name: Cefetamet
• Synonyms: (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, [6R-[6α,7β(Z)]]-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-, Altamet, Antibiotic Ro 15-8074, Cefetamet hydrochloride, Cepime O, Deacetoxycefotaxime, Fr 13300, Ly 97964, Ro 15-8074, Ro 15-8074/005, Ultipime O

Description

Cefetamet is a prodrug, which is hydrolyzed to pivoxil in vivo. It has a chemical stability of four hours at 37°C and can be used as an intermediate for the preparation of cephalosporin esters. Cefetamet is used for the treatment of urinary tract infections due to Escherichia coli and other susceptible organisms. Cefetamet binds to the penicillin-binding proteins in the bacterial cell wall by competitive inhibition, preventing the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division.

• Brand: Biosynth

Chemical properties

• Molecular weight: 397.43 g/mol
• Formula: C₁₄H₁₅N₅O₅S₂
• Purity: Min. 95%