2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methylbromide

CAS: 154057-56-4

Ref. 3D-FC43186

Product Information

• Name: 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methylbromide
• Synonyms: 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-MethylBr, N-7 Br, Quinoline, 3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)-, 3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline, 3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline

Description

Pitavastatin calcium is a member of the statin class of lipid-lowering drugs. It is an inhibitor of HMG-CoA reductase, which is responsible for the conversion of HMG-CoA to mevalonic acid. Pitavastatin calcium has been shown to inhibit cholesterol synthesis and reduce serum LDL levels in humans. The molecular formula for pitavastatin calcium is C32H40O8Ca, with a molecular weight of 576.13 g/mol and an empirical formula of C32H40O8Ca. This drug has a triclinic crystal structure and crystallizes in the form of needles that are x-ray amorphous. The synthesis involves reacting 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl chloride with calcium hydroxide in dry tetrahydrofuran at 0°C to give the title compound after purification by column chromatography on silica gel

• Brand: Biosynth

Chemical properties

• Molecular weight: 355.03719
• Formula: C₁₉H₁₅BrFN
• Purity: Min. 95%