2-Chlorobenzyl bromide
CAS: 611-17-6
Ref. 3D-FC46898
| 1kg | To inquire | ||
| 50g | To inquire | ||
| 100g | To inquire | ||
| 250g | To inquire | ||
| 500g | To inquire |
Product Information
- 1-(Bromomethyl)-2-chlorobenzene
- Benzene, 1-(bromomethyl)-2-chloro-
- Toluene, α-bromo-o-chloro-
- alpha-Bromo-2-chlorotoluene
- o-Chlorobenzyl bromide
- α-Bromo-o-chlorotoluene
2-Chlorobenzyl bromide is a quaternary ammonium salt that is used in the synthesis of acetonitrile and piperidine. 2-Chlorobenzyl bromide has been shown to be an inhibitor of dipeptidyl peptidase IV (DPP-4), which plays a key role in the metabolism of fatty acids. The synthesis of 2-chlorobenzyl bromide can be achieved by reacting acetonitrile with chloroacetone, followed by treatment with potassium hydroxide in methanol. This reaction produces 2-chlorobenzyl chloride, which reacts with sodium methoxide to produce 2-chlorobenzyl bromide and sodium chloride. The preparation of this compound can also be achieved using anion exchange resins. A preparative method for this compound is recrystallization from acetone/hexane mixtures followed by filtration. The centroid of this molecule is
Chemical properties
Technical inquiry about: 3D-FC46898 2-Chlorobenzyl bromide
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