Chloramphenicol palmitate

CAS: 530-43-8

Ref. 3D-FC47229

Product Information

• Name: Chloramphenicol palmitate
• Synonyms: Chloramphenicol a-palmitate, (2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl hexadecanoate, 2-[(Dichloroacetyl)Amino]-3-Hydroxy-3-(4-Nitrophenyl)Propyl Hexadecanoate, <span class="text-smallcaps">D</span>-(-)-Chloramphenicol palmitate, Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, α-palmitate, <span class="text-smallcaps">D</span>-threo-, Ai3-51715, Brn 2826438, CAP-palmitate, Cap-P, Chlorambon, Chloramphenicol monopalmitate, Chloramphenicol monopalmitate (ester), Chloramphenicol palmitate (ester), Chloramphenicol palmitate [JAN], Chloramphenicol α-palmitate, Chloromycetin palmitate, Chloropal, Clorolifarina, D-threo-(-)-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide alpha-palmitate, Detreopal, Hexadecanoic acid, (2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl ester, Hexadecanoic acid, (2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl ester, Hexadecanoic acid, 2-((2,2-dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl ester, (R-(R*,R*))-, Hexadecanoic acid, 2-((dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl ester, (R-(R*,R*))-, Palmitic acid, alpha-ester with D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide, Palmitic acid, ester with chloramphenicol, Palmitic acid, α-ester with <span class="text-smallcaps">D</span>-threo-(-)-2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide, Unii-43Vu4207Nw
• CAS: 530-43-8

Description

Chloramphenicol palmitate is a metastable form of chloramphenicol that is prepared by mixing chloramphenicol with sodium citrate and palmitic acid. It is used in vitro to study the pharmacokinetics of antimicrobial agents. Chloramphenicol palmitate has shown activity against a wide range of bacteria, including gram-positive cocci and some gram-negative bacilli, but not mycobacteria or fungi. This drug inhibits protein synthesis by binding to the 50S ribosomal subunit, preventing the addition of amino acids to the growing peptide chain. The mechanism of action for chloramphenicol palmitate is similar to that of other antibiotics in this class, such as erythromycin and tetracycline.

• Brand: Biosynth

Chemical properties

• Molecular weight: 561.54 g/mol
• Formula: C₂₇H₄₂Cl₂N₂O₆
• Purity: Min. 95%