3-Chloro-5-hydroxybenzoic acid

CAS: 53984-36-4

Ref. 3D-FC51517

Product Information

• Name: 3-Chloro-5-hydroxybenzoic acid
• Synonyms: 3-Chloro-5-hydroxybenzoicacid, 3-Hydroxy-5-chlorobenzoic acid
• CAS: 53984-36-4

Description

3-Chloro-5-hydroxybenzoic acid is a fluorescent compound that has been used to study insulin resistance in rats. Using fluorescence resonance energy transfer, this study found that 3-chloro-5-hydroxybenzoic acid increases insulin sensitivity and decreases blood pressure levels. It is hypothesized that the observed effects are due to an increase in the uptake of 3,5-dihydroxybenzoic acid into cells, which helps regulate the release of nitric oxide from afferent arterioles. Increased nitric oxide leads to vasodilation and increased uptake of glucose by muscle cells. This mechanism may be responsible for the observed decrease in blood pressure and improved insulin sensitivity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 172.56 g/mol
• Formula: C₇H₅ClO₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C7H5ClO3/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,9H,(H,10,11)
• InChI key: InChIKey=RJOLIYHZZKAIET-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(O)cc(Cl)c1